Genetics and Genomics is a Home Area within the UCLA Graduate Programs in Bioscience (GPB).

The main goal of our Home Area is to inspire and educate young scientists in Genetics and Genomics. This is the best time in history to join our field, as fast and cost-effective high-throughput sequencing of multiple types and layers of genomic information are rapidly revolutionizing the role of Genetics and Genomics in medicine and society. Research in Genetics and Genomics is quickly becoming the key source of new insights, better understanding, and targeted treatments of both rare monogenic diseases and common complex diseases such as coronary heart disease, cancer, autism, and diabetes.

The investigators at the Genetics and Genomics Home Area at UCLA are developing networks, systems, and other multilayer approaches combining large data sets and high-throughput information at genomic, transcriptomics, methylomics, proteomics, metabolomics, and phenome level to address the complex architecture and multiple properties leading to human disease. The overall research emphasis of the Genetics and Genomics Home Area at UCLA is on identification and characterization of genes, pathways, and molecular mechanisms converting human health to a disease, utilizing new and state-of-the-art computational, bioinformatics, and molecular genetic and genomics approaches in an integrative way. Investigation across species, in model organisms, and at the cellular level is also utilized to elucidate fundamental biological principles and disease-causing mechanisms. The broad expertise among the researchers in our Home Area extends from plant, animal, and human molecular genetics and genomics to computational biology and systems genomics.

In our research efforts, we highly value interdisciplinary knowledge and institutional, national, and international collaboration as the core of our success. Translation to novel medical preventative tools and targeted treatments is the key research goal of the studies in the Genetics and Genomics Home Area. We anticipate that these translational and multilayer genomics approaches will soon lay a foundation for personalized medicine that allows interpretation of biological high-throughput data at multiple levels through-out an individual’s life in order to tailor preventative measurements and treatments based on his/her genetic, behavioral, and environmental makeup.